We have just started playing around with Adobe Business Catalyst, and it is AMAZING! This is a fully integrated ecommerce system that gives you the power of multiple software suites, easily controlled from one central interface.
It has real-time reporting and analytics built in, data is secure, hosted remotely in data centers in North America, Europe, and the Asia Pacific. In the rare case that you encounter a problem, a wealth of support resources are available right at your fingertips. Sell products online, with integrated order management, shipping and payment collection.
The system does a lot of the things other systems do, just a lot better. With built-in Email Marketing tools, an integrated CRM system and so much more.
It easily integrates with the latest payment gateways, such as MIGS and Pay Pal, which makes it better than osCommerce straight away.
Although traditionally we have shied away from SAS type systems, this one seems to be something special.